STT3A antibody

Catalog No. ABIN5703191

Product Details anti-STT3A Antibody

Target: STT3A (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog A (STT3A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STT3A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Immunogen: STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08355( STT3A Antibody) at dilution of 1:300

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for STT3A

Target: STT3A (STT3, Subunit of The Oligosaccharyltransferase Complex, Homolog A (STT3A))

Alternative Name: STT3A (STT3A Products)

Synonyms: cb437 antibody, wu:fb38c11 antibody, AA408947 antibody, BB081708 antibody, Itm1 antibody, ITM1 antibody, STT3-A antibody, TMC antibody, STT3A, subunit of the oligosaccharyltransferase complex (catalytic) antibody, STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) antibody, STT3A, catalytic subunit of the oligosaccharyltransferase complex antibody, stt3a antibody, Stt3a antibody, STT3A antibody

Background: Synonyms:B5, Integral membrane protein 1, ITM1, STT3 A, STT3A, TMC, Transmembrane protein TMC Background:Catalytic subunit of the N-oligosaccharyl transferase(OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum(ER). SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A.

Gene ID: 3703

UniProt: P46977