GSTa2 antibody
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- Target See all GSTa2 Antibodies
- GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GSTa2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Immunogen
- glutathione S-transferase alpha 2
- Isotype
- IgG
- Top Product
- Discover our top product GSTa2 Primary Antibody
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- Application Notes
- WB : 1:50-1:200 IHC : 1:20-1:200
- Comment
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HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab03687(GSTA2 antibody) at dilution of 1:100
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))
- Alternative Name
- GSTA2 (GSTa2 Products)
- Synonyms
- GSTA1 antibody, GST2 antibody, GSTA2-2 antibody, GTA2 antibody, GTH2 antibody, Gsta1 antibody, Gst2-2 antibody, Gstc-2 antibody, Gstc2 antibody, glutathione S-transferase alpha 2 antibody, glutathione S-transferase antibody, glutathione S-transferase, alpha 2 (Yc2) antibody, GSTA2 antibody, Gsta2 antibody
- Background
- Synonyms:Glutathione S transferase A2, GST class alpha member 2, GST gamma, GST HA subunit 2, GST2, GSTA2, GSTA2 2, GTA2, GTH2 Background:Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti- cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.
- Molecular Weight
- 26 kDa
- Gene ID
- 2939
- UniProt
- P09210
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