RGS10 antibody

Catalog No. ABIN5703290

Product Details anti-RGS10 Antibody

Target: RGS10 (Regulator of G-Protein Signaling 10 (RGS10))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: regulator of G-protein signaling 10

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for RGS10

Target: RGS10 (Regulator of G-Protein Signaling 10 (RGS10))

Alternative Name: RGS10 (RGS10 Products)

Synonyms: MGC82511 antibody, RGS10 antibody, 2310010N19Rik antibody, regulator of G-protein signaling 10 antibody, regulator of G-protein signaling 10 L homeolog antibody, regulator of G protein signaling 10 antibody, regulator of G-protein signalling 10 antibody, RGS10 antibody, rgs10.L antibody, rgs10 antibody, Rgs10 antibody

Background: Synonyms: Background:Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:8774883, PubMed:10608901, PubMed:9353196, PubMed:11443111, PubMed:18434541). Modulates the activity of potassium channels that are activated in response to CHRM2 signaling(PubMed:11443111). Activity on GNAZ is inhibited by palmitoylation of the G-protein(PubMed:9353196).

Gene ID: 6001

UniProt: O43665

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling