SGK3 antibody

Catalog No. ABIN5703403

Product Details anti-SGK3 Antibody

Target: SGK3 (serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGK3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Immunogen: serum/glucocorticoid regulated kinase family, member 3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab07808(SGK3 antibody) at dilution of 1:300

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for SGK3

Target: SGK3 (serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3))

Alternative Name: SGK3 (SGK3 Products)

Synonyms: CISK antibody, SGK2 antibody, SGKL antibody, 2510015P22Rik antibody, A330005P07Rik antibody, Cisk antibody, fy antibody, fz antibody, Sgkl antibody, zgc:162253 antibody, serum/glucocorticoid regulated kinase family member 3 antibody, serum/glucocorticoid regulated kinase 3 antibody, serum/glucocorticoid regulated kinase family, member 3 antibody, serine/threonine-protein kinase Sgk3 antibody, SGK3 antibody, Sgk3 antibody, LOC464217 antibody, sgk3 antibody, LOC100231693 antibody, LOC100343709 antibody, LOC100052030 antibody, LOC100521447 antibody

Background: Synonyms:CISK, SGKL Background:Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na(+) channels: SCNN1A/ENAC and SCN5A, K(+) channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial Ca(2+) channels: TRPV5 and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na(+)/dicarboxylate cotransporter: SLC13A2/NADC1, Na(+)-dependent phosphate cotransporter: SLC34A2/NAPI-2B, amino acid transporters: SLC1A5/ASCT2 and SLC6A19, glutamate transporters: SLC1A3/EAAT1, SLC1A6/EAAT4 and SLC1A7/EAAT5, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase. Plays a role in the regulation of renal tubular phosphate transport and bone density. Phosphorylates NEDD4L and GSK3B. Positively regulates ER transcription activity through phosphorylation of FLII. Negatively regulates the function of ITCH/AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes.

Gene ID: 23678

UniProt: Q96BR1