GPSM1 antibody
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- Target See all GPSM1 Antibodies
- GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GPSM1 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Immunogen
- G-protein signaling modulator 1 (AGS3-like, C. elegans)
- Isotype
- IgG
- Top Product
- Discover our top product GPSM1 Primary Antibody
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- Application Notes
- WB :1:200-1:2000,IF:1:10-1:100,IHC:1:20-1:200
- Comment
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab00221(GPSM1 antibody) at dilution of 1:600
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))
- Alternative Name
- AGS3 (GPSM1 Products)
- Synonyms
- 1810037C22Rik antibody, AW107933 antibody, Ags3 antibody, AGS3 antibody, ags3 antibody, gpsm1 antibody, G-protein signalling modulator 1 (AGS3-like, C. elegans) antibody, G-protein signaling modulator 1 antibody, G protein signaling modulator 1 antibody, G-protein signaling modulator 1 L homeolog antibody, Gpsm1 antibody, GPSM1 antibody, gpsm1.L antibody
- Background
- Synonyms:AGS3, DKFZp727I051, GPSM1 Background:GPSM1, also named as AGS3, is a receptor-independent G protein activator that has been implicated in multiple biological events such as brain development, neuroplasticity and addiction, cardiac function, Golgi structure/function, macroautophagy and metabolism. It contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory(GPR) motifs in its C-terminal half. It has been shown that AGS3 could regulate the orientation of the mitotic spindle, cAMP production, membrane protein transport, and asymmetric cell division by binding preferentially to inactive Gai/o subunits complexed with guanine dinucleotide phosphate(GDP) at multiple G-protein regulatory or GoLoco motif repeats. It also plays an important anti-apoptotic role through enhancing the phosphorylation of cyclic AMP response element-binding protein(p-CREB).
- Molecular Weight
- 72kDa
- UniProt
- Q86YR5
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
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