TEX14 antibody
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- Target See all TEX14 Antibodies
- TEX14 (Testis Expressed 14 (TEX14))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TEX14 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Immunogen
- testis expressed 14
- Isotype
- IgG
- Top Product
- Discover our top product TEX14 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab08609(TEX14 antibody) at dilution of 1:500
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- TEX14 (Testis Expressed 14 (TEX14))
- Alternative Name
- TEX14 (TEX14 Products)
- Synonyms
- CT113 antibody, C85585 antibody, testis expressed 14, intercellular bridge forming factor antibody, testis expressed gene 14 antibody, inactive serine/threonine-protein kinase TEX14 antibody, TEX14 antibody, Tex14 antibody, tex14 antibody, LOC100389169 antibody
- Background
- Synonyms:SGK307 Background:Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro(By similarity).
- Gene ID
- 56155
- UniProt
- Q8IWB6
- Pathways
- Maintenance of Protein Location
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