USP21 antibody
-
- Target See all USP21 Antibodies
- USP21 (Ubiquitin Specific Peptidase 21 (USP21))
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This USP21 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Immunogen
- ubiquitin specific peptidase 21
- Isotype
- IgG
- Top Product
- Discover our top product USP21 Primary Antibody
-
-
- Application Notes
- WB : 1:200-1:2000,IHC:1:20-1:200
- Comment
-
RAW 264.7 cells were subjected to SDS PAGE followed by western blot with FNab09318( USP21 Antibody) at dilution of 1:600
- Restrictions
- For Research Use only
-
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
-
- Target
- USP21 (Ubiquitin Specific Peptidase 21 (USP21))
- Alternative Name
- USP21 (USP21 Products)
- Synonyms
- USP21 antibody, USP16 antibody, USP23 antibody, ESTM28 antibody, Usp16 antibody, Usp23 antibody, W53272 antibody, ubiquitin specific peptidase 21 antibody, USP21 antibody, Usp21 antibody
- Background
- Synonyms:Deubiquitinating enzyme 21, Ubiquitin thiolesterase 21, USP16, USP21, USP23 Background:Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di-and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination(By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates(PubMed:10799498). Deubiquitinates BAZ2A/TIP5 leading to its stabilization(PubMed:26100909).
- Molecular Weight
- 110kDa
- Gene ID
- 27005
- UniProt
- Q9UK80
-