USP34 antibody

Catalog No. ABIN5704533

Product Details anti-USP34 Antibody

Target: USP34 (Ubiquitin Specific Peptidase 34 (USP34))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP34 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: ubiquitin specific peptidase 34

Isotype: IgG

Application Details

Application Notes: WB : 1:500-1:5000,IP:1:200-1:2000,IHC:1:20-1:200

Comment:

human brain tissue were subjected to SDS PAGE followed by western blot with FNab09327(USP34 antibody) at dilution of 1:600

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for USP34

Target: USP34 (Ubiquitin Specific Peptidase 34 (USP34))

Alternative Name: USP34 (USP34 Products)

Synonyms: A530081C03Rik antibody, Murr2 antibody, ubiquitin specific peptidase 34 antibody, Usp34 antibody, USP34 antibody, usp34 antibody

Background: Synonyms:Deubiquitinating enzyme 34, FLJ43910, KIAA0570, KIAA0729, Ubiquitin thiolesterase 34, USP34 Background:Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin(CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.

Molecular Weight: 107kDa

Gene ID: 9736

UniProt: Q70CQ2