USP5 antibody
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- Target See all USP5 Antibodies
- USP5 (Ubiquitin Specific Peptidase 5 (USP5))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This USP5 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Immunogen
- ubiquitin specific peptidase 5 (isopeptidase T)
- Isotype
- IgG1
- Top Product
- Discover our top product USP5 Primary Antibody
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- Application Notes
- WB : 1:500-1:5000
- Comment
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab09341( USP5 Antibody) at dilution of 1:1000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- USP5 (Ubiquitin Specific Peptidase 5 (USP5))
- Alternative Name
- USP5 (USP5 Products)
- Synonyms
- ISOT antibody, AA407472 antibody, ISOT-1 antibody, Ucht antibody, ubiquitin specific peptidase 5 antibody, ubiquitin carboxyl-terminal hydrolase 5 antibody, ubiquitin carboxyl-terminal hydrolase 5, putative antibody, ubiquitin specific protease 5 antibody, ubiquitin specific peptidase 5 (isopeptidase T) antibody, USP5 antibody, CNH02890 antibody, EHI_049940 antibody, CC1G_12961 antibody, MCYG_01862 antibody, CGB_L3600C antibody, PY00546 antibody, Usp5 antibody
- Background
- Synonyms:Deubiquitinating enzyme 5, Isopeptidase T, ISOT, Ubiquitin thiolesterase 5, USP5 Background:Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
- Molecular Weight
- 93kDa
- Gene ID
- 8078
- UniProt
- P45974
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