VPS41 antibody
-
- Target See all VPS41 Antibodies
- VPS41 (Vacuolar Protein Sorting 41 Homolog (VPS41))
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This VPS41 antibody is un-conjugated
-
Application
- ELISA, Western Blotting (WB), Immunofluorescence (IF)
- Immunogen
- vacuolar protein sorting 41 homolog (S. cerevisiae)
- Isotype
- IgG
- Top Product
- Discover our top product VPS41 Primary Antibody
-
-
- Application Notes
- WB :1:200-1:1000,IF:1:10-1:100
- Comment
-
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09442(VPS41 antibody) at dilution of 1:400
- Restrictions
- For Research Use only
-
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
-
- Target
- VPS41 (Vacuolar Protein Sorting 41 Homolog (VPS41))
- Alternative Name
- VPS41 (VPS41 Products)
- Synonyms
- AI317346 antibody, Vam2 antibody, mVam2 antibody, HVPS41 antibody, HVSP41 antibody, hVps41p antibody, RGD1560511 antibody, ATVAM2 antibody, ATVPS41 antibody, T23G18.5 antibody, T23G18_5 antibody, VACUOLAR PROTEIN SORTING 41 antibody, VAM2 antibody, ZIGZAG SUPPRESSOR 2 antibody, ZIP2 antibody, vacuolar protein sorting 41 antibody, Vacuolar assembly protein VPS41 homolog antibody, VPS41, HOPS complex subunit antibody, vacuolar protein sorting 41 antibody, vacuolar protein sorting 41, putative antibody, Vacuolar protein sorting-associated protein 41 homolog antibody, VPS41 HOPS complex subunit antibody, Bm1_34430 antibody, VPS41 antibody, CNI02550 antibody, CC1G_08871 antibody, MCYG_00680 antibody, VDBG_03430 antibody, MGYG_01292 antibody, CGB_H3560C antibody, vps-41 antibody, Vps41 antibody
- Background
- Synonyms:HVPS41, hVps41p, HVSP41, S53, VPS41 Background:Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act in part as a core component of the putative HOPS endosomal tethering complex is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes(PubMed:23351085). Involved in homotypic vesicle fusions between late endosomes and in heterotypic fusions between late endosomes and lysosomes implicated in degradation of endocytosed cargo(PubMed:9159129, PubMed:23167963, PubMed:25445562, PubMed:25908847). Required for fusion of autophagosomes with lysosomes(PubMed:25783203). May link the HOPS complex to endosomal Rab7 via its association with RILP and to lysosomal membranes via its association with ARL8B, suggesting that these interactions may bring the compartments to close proximity for fusion(PubMed:25445562, PubMed:25908847). Involved in the direct trans-Golgi network to late endosomes transport of lysosomal membrane proteins independently of HOPS(PubMed:23322049). Involved in sorting to the regulated secretory pathway presumably implicating the AP-3 adaptor complex(By similarity). May play a role in HOPS-independent function in the regulated secretory pathway(PubMed:24210660).
- Molecular Weight
- 102kDa
- Gene ID
- 27072
- UniProt
- P49754
-