Tescalcin antibody

Catalog No. ABIN5704764

Product Details anti-Tescalcin Antibody

Target: Tescalcin (TESC)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tescalcin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: tescalcin

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab08601(TESC antibody) at dilution of 1:300

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for Tescalcin

Target: Tescalcin (TESC)

Alternative Name: TESC (TESC Products)

Synonyms: TSC antibody, chp3 antibody, CHP3 antibody, 1010001A17Rik antibody, 2410011K10Rik antibody, TE-1 antibody, RGD1566317 antibody, tescalcin antibody, tescalcin L homeolog antibody, tesc antibody, TESC antibody, Tesc antibody, tesc.L antibody

Background: Synonyms:CHP3 Background:Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.

Gene ID: 54997

UniProt: Q96BS2

Pathways: Proton Transport