SLC25A33 antibody

Catalog No. ABIN5704843

Product Details anti-SLC25A33 Antibody

Target: SLC25A33 (Solute Carrier Family 25, Member 33 (SLC25A33))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC25A33 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Immunogen: solute carrier family 25, member 33

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for SLC25A33

Target: SLC25A33 (Solute Carrier Family 25, Member 33 (SLC25A33))

Alternative Name: SLC25A33 (SLC25A33 Products)

Synonyms: BMSC-MCP antibody, PNC1 antibody, 5730438N18Rik antibody, Pnc1 antibody, solute carrier family 25 member 33 antibody, solute carrier family 25, member 33 antibody, SLC25A33 antibody, Slc25a33 antibody

Background: Synonyms: Background:Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria(PubMed:25320081). Transports preferentially uracil, thymine, and cytosine(deoxy)nucleoside di-and triphosphates by an antiport mechanism(PubMed:25320081). Also transports guanine but not adenine(deoxy)nucleotides(PubMed:25320081). Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials(mercury dichloride, mersalyl acid, p-hydroxymercuribenzoate)(PubMed:25320081). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration(PubMed:20453889). Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control of mitochondrial ROS production(PubMed:20453889, PubMed:17596519). Participates in dendritic cell endocytosis and may associate with mitochondrial oxidative phosphorylation(PubMed:14715278).

Gene ID: 84275

UniProt: Q9BSK2