NLRX1 antibody
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- Target See all NLRX1 Antibodies
- NLRX1 (NLR Family Member X1 (NLRX1))
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NLRX1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Immunogen
- NLR family member X1
- Isotype
- IgG
- Top Product
- Discover our top product NLRX1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab05759(NLRX1 antibody) at dilution of 1:1000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- NLRX1 (NLR Family Member X1 (NLRX1))
- Alternative Name
- NLRX1 (NLRX1 Products)
- Synonyms
- CLR11.3 antibody, DLNB26 antibody, NOD26 antibody, NOD5 antibody, NOD9 antibody, BC034204 antibody, RGD1311293 antibody, NLR family member X1 antibody, NLRX1 antibody, nlrx1 antibody, Nlrx1 antibody
- Background
- Synonyms:Caterpiller protein 11.3, CLR11.3, DLNB26, NLR family member X1, NLRX1, NOD26, NOD5, NOD9 Background:Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH(RIG-like helicase)-MAVS interaction(PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species(PubMed:18219313).
- Molecular Weight
- 100-110 kDa
- Gene ID
- 79671
- UniProt
- Q86UT6
- Pathways
- SARS-CoV-2 Protein Interactome
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