MRAP2 antibody

Catalog No. ABIN5705452

Product Details anti-MRAP2 Antibody

Target: MRAP2 (Melanocortin 2 Receptor Accessory Protein 2 (MRAP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRAP2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Immunogen: melanocortin 2 receptor accessory protein 2

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for MRAP2

Target: MRAP2 (Melanocortin 2 Receptor Accessory Protein 2 (MRAP2))

Alternative Name: MRAP2 (MRAP2 Products)

Synonyms: BB633055 antibody, RGD1309873 antibody, C9H6ORF117 antibody, C6orf117 antibody, RP11-51G5.2 antibody, bA51G5.2 antibody, melanocortin 2 receptor accessory protein 2 antibody, Mrap2 antibody, MRAP2 antibody

Background: Synonyms:C6orf117 Background:Modulator of melanocortin receptor 4(MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP(By similarity). May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin(ACTH) to MC2R. May also regulate activity of other melanocortin receptors(MC1R, MC3R and MC5R), however, additional evidences are required in vivo.

Gene ID: 112609

UniProt: Q96G30