TELO2 antibody
-
- Target See all TELO2 Antibodies
- TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This TELO2 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Immunogen
- TEL2, telomere maintenance 2, homolog (S. cerevisiae)
- Isotype
- IgG2a
- Top Product
- Discover our top product TELO2 Primary Antibody
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
-
A431 cells were subjected to SDS PAGE followed by western blot with FNab08592(TELO2 antibody) at dilution of 1:500
- Restrictions
- For Research Use only
-
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
-
- Target
- TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))
- Alternative Name
- TELO2 (TELO2 Products)
- Synonyms
- RGD1305553 antibody, 1200003M09Rik antibody, AI415602 antibody, Tel2 antibody, mKIAA0683 antibody, CLK2 antibody, TEL2 antibody, telomere maintenance 2 antibody, Telo2 antibody, TELO2 antibody
- Background
- Synonyms:KIAA0683 Background:Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.
- Gene ID
- 9894
- UniProt
- Q9Y4R8
-