SH3PXD2A antibody

Catalog No. ABIN5705579

Product Details anti-SH3PXD2A Antibody

Target: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3PXD2A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: SH3 and PX domains 2A

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab07836(SH3PXD2A antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for SH3PXD2A

Target: SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))

Alternative Name: SH3PXD2A (SH3PXD2A Products)

Synonyms: FISH antibody, SH3MD1 antibody, TKS5 antibody, 2310014D11Rik antibody, AA589508 antibody, AI256723 antibody, AI413738 antibody, C230050L11 antibody, EG329070 antibody, Fish antibody, Gm5098 antibody, Sh3md1 antibody, TSK5 antibody, Tks5 antibody, sh3pxd2a antibody, si:dkey-82d4.2 antibody, SH3 and PX domains 2A antibody, SH3 and PX domains 2Aa antibody, SH3PXD2A antibody, Sh3pxd2a antibody, sh3pxd2aa antibody

Background: Synonyms:FISH, KIAA0418, SH3MD1, TKS5 Background:Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases(ADAMs), NADPH oxidases(NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1-or NOX3-dependent reactive oxygen species(ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.

Gene ID: 9644

UniProt: Q5TCZ1