OMA1 antibody

Catalog No. ABIN5705724

Product Details anti-OMA1 Antibody

Target: OMA1 (OMA1 Zinc Metallopeptidase Homolog (OMA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OMA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: OMA1 homolog, zinc metallopeptidase (S. cerevisiae)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for OMA1

Target: OMA1 (OMA1 Zinc Metallopeptidase Homolog (OMA1))

Alternative Name: OMA1 (OMA1 Products)

Synonyms: 2010001O09Rik antibody, DAB1 antibody, MPRP-1 antibody, YKR087C antibody, ZMPOMA1 antibody, peptidase antibody, RGD1304821 antibody, oma1 antibody, OMA1 zinc metallopeptidase antibody, si:ch73-215a11.1 antibody, olfactory receptor 4K2 antibody, OMA1 antibody, Oma1 antibody, si:ch73-215a11.1 antibody, LOC531304 antibody

Background: Synonyms:MPRP1 Background:Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.

Molecular Weight: 60 kDa

Gene ID: 115209

UniProt: Q96E52