Recombinant Insulin antibody

Catalog No. ABIN5707534

The Rabbit Monoclonal anti-Insulin antibody (Clone IRDN-1980R) (ABIN5707534) specifically detects Insulin in IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for Recombinant Insulin antibody (ABIN5707534)

Target: Insulin (INS)

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Insulin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: IRDN-1980R

Product Details anti-Insulin Antibody

Purpose: Recombinant INS Antibody / Insulin

Purification: Protein A affinity chromatography

Immunogen: Purified pig insulin conjugated to KLH was used as the immunogen for the recombinant INS antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant INS antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant INS antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Insulin

Target: Insulin (INS)

Alternative Name: INS

Background: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. [UniProt]

UniProt: P01308

Pathways: NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation