PDK2 antibody (AA 81-177)
Quick Overview for PDK2 antibody (AA 81-177) (ABIN5708185)
Target
See all PDK2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 81-177
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Cross-Reactivity (Details)
- Expected species reactivity: Human
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Purification
- Antigen affinity purified
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Immunogen
- A recombinant human partial protein corresponding to amino acids V81-D177 was used as the immunogen for the PDK2 antibody.
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Isotype
- IgG
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anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 187-276) antibody
PDK2 Reactivity: Human WB, ELISA, IHC (p), RNAi Host: Mouse Monoclonal 2G1 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 155-379) antibodyPDK2 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 178-404) antibodyPDK2 Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 3F2D7 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (C-Term) antibodyPDK2 Reactivity: Human, Mouse, Rat WB, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 128-407) antibodyPDK2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) antibodyPDK2 Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal RB23089 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 78-107), (N-Term) antibodyPDK2 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB34663 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 378-407), (C-Term) antibodyPDK2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB03037 unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 128-407) antibodyPDK2 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2) (AA 379-392), (C-Term) antibodyPDK2 Reactivity: Human, Mouse, Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
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Application Notes
- Optimal dilution of the PDK2 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL
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Restrictions
- For Research Use only
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- -20 °C
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Storage Comment
- After reconstitution, the PDK2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
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Alternative Name
- PDK2 / Pyruvate dehydrogenase kinase 2
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Background
- PDK2 (Pyruvate Dehydrogenase Kinase Isoenzyme 2), is an enzyme that in humans is encoded by the PDK2 gene. This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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UniProt
- Q15119
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Pathways
- PI3K-Akt Signaling, RTK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
Target
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