CES1 antibody

Catalog No. ABIN5708325

Product Details anti-CES1 Antibody

Target: CES1 (Carboxylesterase 1 (CES1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CES1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids E99-A206 was used as the immunogen for the Carboxylesterase 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Carboxylesterase 1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Carboxylesterase 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for CES1

Target: CES1 (Carboxylesterase 1 (CES1))

Alternative Name: Carboxylesterase 1 / CES1 (CES1 Products)

Synonyms: ACAT antibody, CE-1 antibody, CEH antibody, CES2 antibody, HMSE antibody, HMSE1 antibody, PCE-1 antibody, REH antibody, SES1 antibody, TGH antibody, hCE-1 antibody, CESDD1 antibody, CES1 antibody, CES-K1 antibody, APLE antibody, PMPMEase antibody, CES antibody, carboxylesterase 1 antibody, liver carboxylesterase 1 antibody, liver carboxylesterase antibody, carboxylesterase 1 (monocyte/macrophage serine esterase 1) antibody, CES1 antibody, CpipJ_CPIJ013026 antibody, CpipJ_CPIJ016339 antibody, LOC100009551 antibody, LOC454097 antibody, LOC699486 antibody, LOC100050915 antibody

Background: Liver carboxylesterase 1 also known as carboxylesterase 1 (CES1, hCE-1 or CES1A1) is an enzyme that in humans is encoded by the CES1 gene. This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

UniProt: P23141

Pathways: Monocarboxylic Acid Catabolic Process