RTEL1 antibody

Catalog No. ABIN5708351

Product Details anti-RTEL1 Antibody

Target: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RTEL1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Cross-Reactivity (Details): Expected species reactivity: Human

Purification: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids R651-M756 was used as the immunogen for the RTEL1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the RTEL1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the RTEL1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for RTEL1

Target: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Alternative Name: RTEL1 (RTEL1 Products)

Synonyms: F18B13.3 antibody, F18B13_3 antibody, C20orf41 antibody, DKCB5 antibody, NHL antibody, RTEL antibody, bK3184A7.3 antibody, AI451565 antibody, AW540478 antibody, Rtel antibody, RGD1306721 antibody, zgc:113114 antibody, regulator of telomere elongation helicase 1 antibody, RAD3-like DNA-binding helicase protein antibody, RTEL1 antibody, rtel1 antibody, AT1G79950 antibody, LOC100286037 antibody, Rtel1 antibody

Background: The RTEL1 gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q9NZ71