ITGA5 antibody

Catalog No. ABIN5708438

Product Details anti-ITGA5 Antibody

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogen: A recombinant human partial protein corresponding to amino acids F42-A263 was used as the immunogen for the ITGA5 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ITGA5 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the ITGA5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Alternative Name: Integrin alpha 5 / ITGA5 (ITGA5 Products)

Synonyms: ITGA5 antibody, Cd49e antibody, Fnra antibody, VLA5 antibody, CD49e antibody, FNRA antibody, VLA5A antibody, Itga5_retired antibody, integrin subunit alpha 5 antibody, integrin alpha 5 (fibronectin receptor alpha) antibody, ITGA5 antibody, Itga5 antibody

Background: Integrin alpha-5, also known as FNRA or VLA5A, is a protein that in humans is encoded by the ITGA5 gene. The product of this gene belongs to the integrin alpha chain family. Integrins are integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

UniProt: P08648

Pathways: Integrin Complex