EOMES antibody

Catalog No. ABIN5708445

Product Details anti-EOMES Antibody

Target: EOMES (Eomesodermin (EOMES))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EOMES antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): Expected species reactivity: Human

Purification: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids T310-D532 was used as the immunogen for the EOMES antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the EOMES antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the EOMES antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for EOMES

Target: EOMES (Eomesodermin (EOMES))

Alternative Name: EOMES / Eomesodermin / TBR2 (EOMES Products)

Synonyms: TBR2 antibody, eom antibody, eomes antibody, EOMES antibody, xeomes antibody, tbr2 antibody, C77258 antibody, TBR-2 antibody, Tbr2 antibody, eomesodermin antibody, eomesodermin homolog a antibody, eomesodermin L homeolog antibody, EOMES antibody, eomesa antibody, Eomes antibody, eomes.L antibody, eomes antibody

Background: Eomesodermin also known as T-box brain protein 2 (Tbr2) is a protein that in humans is encoded by the EOMES gene. This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants.

UniProt: O95936

Pathways: Stem Cell Maintenance