MKS1
Reactivity: Human
WB, ELISA, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
The stated application concentrations are suggested starting points. Titration of the MKS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. WB: 1:1000-1:2000
Restrictions
For Research Use only
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the MKS1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
MKS1
(Meckel Syndrome, Type 1 (MKS1))
Alternative Name
MKS1 / Meckel syndrome type 1 protein (MKS1 Products)
Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology.