CYP26A1 antibody (AA 485-496)

Catalog No. ABIN574066

Product Details anti-CYP26A1 Antibody

Target: CYP26A1 (Cytochrome P450, Family 26, Subfamily A, Polypeptide 1 (CYP26A1))

Binding Specificity: AA 485-496

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CYP26A1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human CYP26A1. This antibody is expected to recognize both reported isoforms (NP_000774.2, NP_476498.1)

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Marmoset (92%) Rat, Hamster, Elephant, Panda, Bat, Dog, Rabbit (83%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-NLPARFTHFHGE from an internal region of human CYP26A1 (NP_000774.2, NP_476498.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%), Marmoset (92%), Rat, Hamster, Elephant, Panda, Bat, Dog, Rabbit (83%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3.75 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3.75 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CYP26A1

Target: CYP26A1 (Cytochrome P450, Family 26, Subfamily A, Polypeptide 1 (CYP26A1))

Alternative Name: CYP26 / CYP26A1 (CYP26A1 Products)

Synonyms: CP26 antibody, CYP26 antibody, P450RAI antibody, P450RAI1 antibody, Cyp26 antibody, P450RA antibody, RAH antibody, RACE antibody, XCYP26A1 antibody, cyp26 antibody, xCYP26 antibody, cp26 antibody, p450rai antibody, p450rai1 antibody, CYP26A antibody, cb24 antibody, id:ibd5061 antibody, wu:fb81e05 antibody, cytochrome P450 family 26 subfamily A member 1 antibody, cytochrome P450, family 26, subfamily a, polypeptide 1 antibody, cytochrome P450 family 26 subfamily A member 1 S homeolog antibody, cytochrome P450 family 26 subfamily A member 1 L homeolog antibody, cytochrome P450, family 26, subfamily A, polypeptide 1 antibody, CYP26A1 antibody, Cyp26a1 antibody, cyp26a1.S antibody, cyp26a1.L antibody, cyp26a1 antibody

Background: Name/Gene ID: CYP26A1
Family: Cytochrome P450

Synonyms: CYP26A1, CYP26, Cytochrome P450 26A1, Cytochrome P450RAI, HP450RAI, p450RAI, p450RAI1, Retinoic acid 4-hydroxylase, CP26

Gene ID: 1592

NCBI Accession: NP_000774, NP_476498

UniProt: O43174

Pathways: Retinoic Acid Receptor Signaling Pathway, Monocarboxylic Acid Catabolic Process