PR (pSer400) antibody

Catalog No. ABIN5956283

Product Details

Target: PR

Binding Specificity: pSer400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Specificity: NR3C3,Nuclear receptor subfamily 3 group C member 3,PGR,PR,PRA,PRB,PRGR,Progesterone receptor,Progestin receptor form A,Progestin receptor form B

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human PR around the phosphorylation site of S400.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF 1:200-1:1000, ELISA 1:5000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol  pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details

Target: PR

Synonyms: SPC antibody, proline rich protein gene cluster antibody, PR@ antibody

Background: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation.Isoform A: inactive in stimulating c-Src/MAPK signaling on hormone stimulation.Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone.

Molecular Weight: 99kDa

Gene ID: 5241

UniProt: P06401