c-FOS antibody

Catalog No. ABIN5958109

Product Details anti-c-FOS Antibody

Target: c-FOS (c-Fos) (c-Fos)

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This c-FOS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Activator protein 1,AP 1,C FOS,Cellular oncogene c fos,Cellular oncogene fos,FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS),FBJ murine osteosarcoma viral oncogene homolog,FBJ murine osteosarcoma viral v fos oncogene homolog,FBJ Osteosarcoma Virus,FOS,FOS protein,FOS,G0 G1 switch regulatory protein 7,G0/G1 switch regulatory protein 7,G0S7,Oncogene FOS,p55,proto oncogene c Fos,Proto oncogene protein c fos,Proto-oncogene c-Fos,v fos FBJ murine osteosarcoma viral oncogene homolog

Purification: Protein A purification

Immunogen: Recombinant Protein

Clone: 0

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300 ELISA 1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for c-FOS

Target: c-FOS (c-Fos) (c-Fos)

Alternative Name: c-Fos (c-Fos Products)

Synonyms: AP-1 antibody, C-FOS antibody, p55 antibody, c-fos antibody, D12Rfj1 antibody, cFos antibody, cFOS antibody, fos antibody, Fos proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene antibody, proto-oncogene c-Fos-like antibody, FOS antibody, Fos antibody, LOC101078177 antibody

Background: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.

Gene ID: 2353

UniProt: P01100

Pathways: S100 Proteins