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DNMT3B antibody
DNMT3B
Reactivity: Human, Chicken
WB, ELISA, IF, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DNMT3B Antibody
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Target
See all DNMT3B Antibodies
DNMT3B
(DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
Reactivity
All reactivities for DNMT3B antibodies
Human, Chicken
Host
All hosts for DNMT3B antibodies
Rabbit
Clonality
All clonalities for DNMT3B antibodies
Polyclonal
Conjugate
All conjugates for DNMT3B antibodies
This DNMT3B antibody is un-conjugated
Application
All applications for DNMT3B antibodies
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
Cytosine 5methyltransferase 3B,DNA,DNA (cytosine 5) methyltransferase 3 beta,DNA (cytosine 5)-methyltransferase 3B,DNA (cytosine-5)-methyltransferase 3B,DNA methyltransferase HsaIIIB,DNA MTase HsaIIIB,DNM3B,Dnmt3b,EC 2.1.1.37,ICF,ICF1,M.HsaIIIB,MGC124407,RP23-89H14.3
Purification
Affinity purification
Immunogen
Synthesized peptide derived from the N-terminal region of human Dnmt3b
Isotype
IgG
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Discover our top product DNMT3B Primary Antibody
Alternatives
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Application Details
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Application Notes
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Restrictions
For Research Use only
Handling
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Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for DNMT3B
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Target
DNMT3B
(DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
Alternative Name
Dnmt3b (DNMT3B Products )
Synonyms
DNMT3B antibody, LOC100218113 antibody, ICF antibody, ICF1 antibody, M.HsaIIIB antibody, MmuIIIB antibody, cb91 antibody, dnmt3bl antibody, dnmt7 antibody, sb:cb91 antibody, wu:fb16h07 antibody, DNA methyltransferase 3 beta antibody, DNA methyltransferase 3B antibody, DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a antibody, DNMT3B antibody, Dnmt3b antibody, dnmt3b antibody, dnmt3ba antibody
Background
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.
Molecular Weight
96kDa
Gene ID
1789
UniProt
Q9UBC3
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