BTK antibody (pTyr551)

Catalog No. ABIN5960622

Product Details anti-BTK Antibody

Target: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Binding Specificity: pTyr551

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTK antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Agammaglobulinaemia tyrosine kinase,AGMX 1,AGMX1,AT,ATK,B cell progenitor kinase,B-cell progenitor kinase,BPK,Bruton agammaglobulinemia tyrosine kinase,Bruton tyrosine kinase,Bruton's Tyrosine Kinase,Btk,BTK,dominant-negative kinase-deficient Brutons tyrosine kinase,IMD 1,IMD1,MGC126261,MGC126262,OTTHUMP00000063593,PSCTK 1,PSCTK1,truncated Bruton agammaglobulinemia tyrosine kinase,Tyrosine protein kinase BTK,Tyrosine-protein kinase BTK,tyrosine-protein kinase BTK isoform (lacking exon 14,XLA

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human Btk around the phosphorylation site of Tyr551

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA 1:40000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BTK

Target: BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))

Alternative Name: Btk (BTK Products)

Synonyms: BTK antibody, atk antibody, bpk antibody, xla antibody, imd1 antibody, agmx1 antibody, psctk1 antibody, AGMX1 antibody, AT antibody, ATK antibody, BPK antibody, IMD1 antibody, PSCTK1 antibody, XLA antibody, AI528679 antibody, xid antibody, Bruton tyrosine kinase antibody, Bruton agammaglobulinemia tyrosine kinase antibody, BTK antibody, btk antibody, Btk antibody

Background: Plays a crucial role in B-cell ontogeny. Transiently phosphorylates GTF2I on tyrosine residues in response to B-cell receptor cross-linking. Required for the formation of functional ARID3A DNA-binding complexes.

Molecular Weight: 76kDa

Gene ID: 695

UniProt: Q06187

Pathways: Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling