CXCR2 antibody

Catalog No. ABIN5960775

Product Details anti-CXCR2 Antibody

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: C C,C C CKR 1,C-X-C chemokine receptor type 1,CCCKR1,CD 181,CD128,CD181,CD181 antigen,CDw128a,Chemokine (C X C motif) receptor 1,Chemokine (C X C) receptor 1,Chemokine receptor 1,CKR 1,CMKAR1,CXC-R1,CXCR 1,CXCR-1,CXCR1,CXCR1,High affinity interleukin 8 receptor A,High affinity interleukin-8 receptor A,IL 8 receptor type 1,IL 8R A,IL-8 receptor type 1,IL-8R A,IL8 receptor,IL8 receptor type 1,IL8R1,IL8RA,IL8RBA,Interleukin 8 receptor alpha,Interleukin 8 receptor type 1,Interleukin 8 receptor type A

Purification: Affinity purification

Immunogen: Synthetic peptide from human protein

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200, ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CXCR2

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Alternative Name: IL-8RA (CXCR2 Products)

Synonyms: CD182 antibody, CDw128b antibody, CMKAR2 antibody, IL8R2 antibody, IL8RA antibody, IL8RB antibody, CXC-R2 antibody, CXCR-2 antibody, CD128 antibody, CDw128 antibody, Cmkar2 antibody, Gpcr16 antibody, IL-8Rh antibody, IL-8rb antibody, Il8rb antibody, mIL-8RH antibody, C-X-C motif chemokine receptor 2 antibody, chemokine (C-X-C motif) receptor 2 antibody, Cxcr2 antibody, CXCR2 antibody

Background: The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.

Gene ID: 3577

UniProt: P25024

Pathways: cAMP Metabolic Process