DUSP10 antibody

Catalog No. ABIN5963303

Product Details anti-DUSP10 Antibody

Target: DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP10 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human DUSP10

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DUSP10

Target: DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))

Alternative Name: MKP-5 (DUSP10 Products)

Synonyms: DUSP10 antibody, MKP-5 antibody, MKP5 antibody, 2610306G15Rik antibody, AI158871 antibody, Mkp-5 antibody, Mkp5 antibody, dual specificity phosphatase 10 antibody, DUSP10 antibody, Dusp10 antibody

Background:

Synonyms: Dual specificity phosphatase 10,Dual specificity phosphatase MKP 5,Dual specificity phosphatase MKP5,Dual specificity protein phosphatase 10,DUS10,DUSP 10,DUSP10,DUSP10 protein,MAP kinase phosphatase 5,Mitogen activated protein kinase phosphatase 5,Mitogen-activated protein kinase phosphatase 5,MKP 5,MKP-5,MKP5,Serine/threonine specific protein phosphatase

Background: Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 53kDa

Calculated_MW: 16kDa/52kDa

Gene ID: 11221

UniProt: Q9Y6W6