DAD1 antibody
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- Target See all DAD1 Antibodies
- DAD1 (Defender Against Cell Death 1 (DAD1))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DAD1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- A synthetic peptide of human DAD1
- Isotype
- IgG
- Top Product
- Discover our top product DAD1 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- DAD1 (Defender Against Cell Death 1 (DAD1))
- Alternative Name
- DAD1 (DAD1 Products)
- Synonyms
- NV18456 antibody, dad1 antibody, DAD1 antibody, ost2 antibody, DAD-1 antibody, si:ch211-9d9.5 antibody, OST2 antibody, AI323713 antibody, DEFENDER AGAINST APOPTOTIC DEATH 1 antibody, F3C3.14 antibody, F3C3_14 antibody, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 antibody, defender against cell death 1 antibody, hypothetical protein antibody, defender against cell death 1 S homeolog antibody, Defender against death (DAD family) protein antibody, false DAD1 antibody, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad-1 antibody, LOC100115214 antibody, DAD1 antibody, dad1 antibody, CC1G_00458 antibody, CpipJ_CPIJ003512 antibody, PGTG_09898 antibody, Dad1 antibody, dad1.S antibody, ATDAD1 antibody, fdad1 antibody, dad-1 antibody
- Background
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Synonyms: DAD 1,DAD-1,dad1,DAD1,Defender against cell death 1,Dolichyl diphosphooligosaccharide protein glycosyltransferase subunit DAD1,Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1,Oligosaccharyl transferase subunit DAD1,OST 2,OST2
Background: DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes.
- Molecular Weight
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Observed_MW: 22kDa
Calculated_MW: 12kDa
- Gene ID
- 1603
- UniProt
- P61803
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