GUCY1A1 antibody

Catalog No. ABIN5963492

Product Details anti-GUCY1A1 Antibody

Target: GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCY1A1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human GUCY1A3

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:3000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GUCY1A1

Target: GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))

Alternative Name: GUCY1A3 (GUCY1A1 Products)

Synonyms: GC-SA3 antibody, GUC1A3 antibody, GUCA3 antibody, GUCSA3 antibody, GUCY1A1 antibody, 1200016O07Rik antibody, Gucy1a1 antibody, SGC antibody, im:7136149 antibody, sgc1a1 antibody, zgc:112159 antibody, gucy1a3 antibody, guanylate cyclase 1 soluble subunit alpha antibody, guanylate cyclase 1, soluble, alpha 3 antibody, guanylate cyclase 1 soluble subunit alpha 3 antibody, soluble guanylyl cyclase alpha subunit antibody, GUCY1A3 antibody, Gucy1a3 antibody, gucy1a3 antibody

Background:

Synonyms: GC S alpha 1,GC SA3,GCS alpha 1,GCS alpha 3,GCS-alpha-1,GCS-alpha-3,GCYA3,Guanylate cyclase 1 soluble alpha 3,Guanylate cyclase soluble subunit alpha 1,Guanylate cyclase soluble subunit alpha 3,Guanylate cyclase soluble subunit alpha-3,Guanylate cyclase,nitric oxide-sensitive,alpha-1 subunit,Guc1a1,GUC1A3,GUCA3,GUCSA3,Gucy1a1,Gucy1a3,MYMY6,nitric oxide-sensitive Guanylate cyclase,alpha-1 subunit,NOGC,alpha-1 subunit,Soluble guanylate cyclase large subunit

Background: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 77kDa

Calculated_MW: 70kDa/77kDa

Gene ID: 2982

UniProt: Q02108

Pathways: Myometrial Relaxation and Contraction