TIM3 antibody
-
- Target See all TIM3 (TIM 3) Antibodies
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This TIM3 antibody is un-conjugated
-
Application
- Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human TIM-3/HAVCR2 (NP_116171.3).
- Isotype
- IgG
- Top Product
- Discover our top product TIM 3 Primary Antibody
-
-
- Application Notes
- IHC 1:50-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
- Alternative Name
- TIM-3/HAVCR2 (TIM 3 Products)
- Synonyms
- HAVCR2 antibody, MGC140131 antibody, HAVcr-2 antibody, KIM-3 antibody, TIM3 antibody, TIMD-3 antibody, TIMD3 antibody, Tim-3 antibody, TIM-3 antibody, Tim3 antibody, Timd3 antibody, tim3 antibody, hepatitis A virus cellular receptor 2 antibody, HAVCR2 antibody, Havcr2 antibody
- Target Type
- Virus
- Background
- The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
- Molecular Weight
-
Observed_MW: 36kDa
Calculated_MW: 16kDa/33kDa
- Gene ID
- 84868
- UniProt
- Q8TDQ0
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
-