ALAS1 antibody

Catalog No. ABIN5965212

Product Details anti-ALAS1 Antibody

Target: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALAS1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human ALAS1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ALAS1

Target: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Alternative Name: ALAS1 (ALAS1 Products)

Synonyms: ALAS antibody, ALAS3 antibody, ALASH antibody, MIG4 antibody, ALAS-N antibody, Alas-1 antibody, Alas-h antibody, ALAS-H antibody, ALASN antibody, ALAS1 antibody, wu:fb58d01 antibody, wu:fi12g09 antibody, 5'-aminolevulinate synthase 1 antibody, aminolevulinic acid synthase 1 antibody, alanyl-tRNA synthetase protein antibody, aminolevulinate, delta-, synthase 1 antibody, ALAS1 antibody, Alas1 antibody, alas1 antibody, alas1.S antibody, alaS1 antibody

Background:

Synonyms: 5 aminolevulinate synthase ,5 aminolevulinate synthase nonspecific mitochondrial,5 aminolevulinic acid synthase,5-aminolevulinate synthase,5-aminolevulinic acid synthase 1,Alas 1,ALAS 3,ALAS,ALAS H,ALAS HOUSEKEEPING TYPE,ALAS N,ALAS-H,alaS1,ALAS3,ALASH,Aminolevulinate delta synthase 1,Aminolevulinic acid synthase 1,Delta ALA synthetase,Delta aminolevulinate synthase,Delta-ALA synthase 1,Delta-aminolevulinate synthase 1,HEM1,MIG 4,MIG4,Migration inducing protein 4,mitochondrial,nonspecific

Background: This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight:

Observed_MW: 70kDa

Calculated_MW: 12kDa/70kDa

Gene ID: 211

UniProt: P13196

Pathways: Regulation of Lipid Metabolism by PPARalpha