Mps1 antibody

Catalog No. ABIN5965837

Product Details anti-Mps1 Antibody

Target: Mps1 (TTK)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mps1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human TTK

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Mps1

Target: Mps1 (TTK)

Alternative Name: TTK (TTK Products)

Synonyms: CT96 antibody, ESK antibody, MPH1 antibody, MPS1 antibody, MPS1L1 antibody, PYT antibody, AL022661 antibody, Esk1 antibody, Mps1 antibody, esk antibody, mps1 antibody, ncp antibody, Ttk protein kinase antibody, TTK protein kinase antibody, ttk protein kinase antibody, Ttk antibody, TTK antibody, ttk antibody

Background:

Synonyms: cancer/testis antigen 96,CT96,Dual specificity protein kinase TTK,ECSTY kinase,ESK,FLJ38280,hMPS1,Monopolar Spindle 1 Like 1 ,MPH1,Mps 1,MPS1L1,Phosphotyrosine Picked Threonine Kinase,Phosphotyrosine picked threonine-protein kinase,PYT,RP3-357D13.2,ttk,TTK Protein Kinase,TTK

Background: This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 105kDa

Calculated_MW: 96kDa/97kDa

Gene ID: 7272

UniProt: P33981