Spartan antibody
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- Target See all Spartan (C1orf124) products
- Spartan (C1orf124) (Chromosome 1 Open Reading Frame 124 (C1orf124))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Spartan antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human SPRTN
- Isotype
- IgG
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- Application Notes
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Spartan (C1orf124) (Chromosome 1 Open Reading Frame 124 (C1orf124))
- Alternative Name
- SPRTN (C1orf124 Products)
- Synonyms
- Spartan antibody, c1orf124 antibody, C1orf124 antibody, DDDL1880 antibody, DVC1 antibody, PRO4323 antibody, dJ876B10.3 antibody, C28H1orf124 antibody, SprT-like N-terminal domain antibody, sprtn antibody, SPRTN antibody
- Background
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Synonyms: C1orf124,CA124,Chromosome 1 open reading frame 124 ,DDDL1880,dJ876B10.3,PRO4323,RP5-876B10.3,Spartan,SprT-like domain at the N terminus,SprT-like N-terminal domain,Zinc finger RAD18 domain-containing protein C1orf124
Background: The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.
- Molecular Weight
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Observed_MW: 60kDa
Calculated_MW: 24kDa/29kDa/55kDa
- Gene ID
- 83932
- UniProt
- Q9H040
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