NAD-ME antibody

Catalog No. ABIN5968030

Product Details anti-NAD-ME Antibody

Target: NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAD-ME antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human ME2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NAD-ME

Target: NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))

Alternative Name: ME2 (NAD-ME Products)

Synonyms: ODS1 antibody, AW120568 antibody, D030040L20Rik antibody, NAD-ME antibody, zgc:100941 antibody, malic enzyme 2 antibody, malic enzyme 2, NAD(+)-dependent, mitochondrial antibody, malic enzyme 2, NAD(+)-dependent, mitochondrial S homeolog antibody, ME2 antibody, Me2 antibody, me2.S antibody, me2 antibody

Background:

Synonyms: Malate dehydrogenase,Malic enzyme 2,Malic enzyme 2 mitochondrial,Malic enzyme 2 NAD(+) dependent mitochondrial,Malic enzyme mitochondrial,Malic enzyme NAD(+) dependent mitochondrial,MAOM,ME 2,ME2,mitochondrial,NAD dependent malic enzyme mitochondrial,NAD ME,NAD-dependent malic enzyme,NAD-ME,ODS1,Pyruvic malic carboxylase

Background: This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.

Molecular Weight:

Observed_MW: 65kDa

Calculated_MW: 53kDa/65kDa

Gene ID: 4200

UniProt: P23368

Pathways: Production of Molecular Mediator of Immune Response