C8B antibody

Catalog No. ABIN5968174

Product Details anti-C8B Antibody

Target: C8B (Complement Component 8, beta Polypeptide (C8B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C8B antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human C8B

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for C8B

Target: C8B (Complement Component 8, beta Polypeptide (C8B))

Alternative Name: C8 beta (C8B Products)

Synonyms: C82 antibody, 4930439B20Rik antibody, AI595927 antibody, complement C8 beta chain antibody, complement component 8, beta polypeptide antibody, C8B antibody, C8b antibody, c8b antibody

Background:

Synonyms: C8b,CO8B,Complement component 8 beta polypeptide,Complement component 8 subunit beta,Complement component C8 beta chain

Background: This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 67kDa

Calculated_MW: 67kDa

Gene ID: 732

UniProt: P07358

Pathways: Complement System