EDAR antibody

Catalog No. ABIN5968396

Product Details anti-EDAR Antibody

Target: EDAR (Ectodysplasin A Receptor (EDAR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDAR antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human EDAR

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EDAR

Target: EDAR (Ectodysplasin A Receptor (EDAR))

Alternative Name: EDAR (EDAR Products)

Synonyms: rs3 antibody, edar antibody, EDAR antibody, MGC88893 antibody, DL antibody, ECTD10A antibody, ECTD10B antibody, ED1R antibody, ED3 antibody, ED5 antibody, EDA-A1R antibody, EDA1R antibody, EDA3 antibody, HRM1 antibody, dl antibody, RGD1561714 antibody, ectodysplasin A receptor antibody, ectodysplasin-A receptor antibody, edar antibody, EDAR antibody, Edar antibody

Background:

Synonyms: Anhidrotic ectodysplasin receptor 1,DL,Downless (mouse) homolog,Downless homolog,Downless mouse homolog of,ECTD10A,ECTD10B,Ectodermal dysplasia receptor,Ectodysplasin 1 anhidrotic receptor,Ectodysplasin A receptor,Ectodysplasin A1 isoform receptor,Ectodysplasin-A receptor,ED 1R,ED 3,ED 5,ED1R,ED3,ED5,EDA 1R,EDA 3,EDA A1 receptor,EDA A1R,EDA-A1 receptor,EDA1R,EDA3,Edar,EDAR,HRM1,Tumor necrosis factor receptor superfamily member EDAR

Background: This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

Molecular Weight:

Observed_MW: 45kDa

Calculated_MW: 48kDa/51kDa

Gene ID: 10913

UniProt: Q9UNE0

Pathways: Tube Formation, Ubiquitin Proteasome Pathway