Insulin Receptor antibody (AA 59-75)

Catalog No. ABIN599777

The Rabbit Polyclonal anti-Insulin Receptor antibody has been validated for WB, IHC and IHC (p). It is suitable to detect Insulin Receptor in samples from Human, Mouse, Rat, Dog, Monkey, Horse and Cow.

Quick Overview for Insulin Receptor antibody (AA 59-75) (ABIN599777)

Target: Insulin Receptor (INSR)

Reactivity: Human, Mouse, Rat, Dog, Monkey, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Insulin Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Insulin Receptor Antibody

Binding Specificity: AA 59-75

Specificity: Recognizes human Insulin receptor subunit alpha at 156kD. Species cross-reactivity: canine, rat. Sequence Homology: mouse.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Horse (100%) Bat, Opossum, Turkey, Chicken (88%).

Purification: Affinity purified

Immunogen: Synthetic peptide corresponding to aa59-75, HLQILLMFKTRPEDFRD to human Insulin receptor (isoform Long). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Horse (100%), Bat, Opossum, Turkey, Chicken (88%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (1 - 2 μg/mL), WB (0.75 μg/mL)

Usage: Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 0.75 μg/mL. Immunohistochemistry (paraffin and formalin): 1-2 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile distilled water

Concentration: Lot specific

Buffer: Lyophilized from 5 mg BSA, 0.9 mg sodium chloride, 0.2 mg sodium phosphate, 0.05 mg Thimerosal, 0.05 mg sodium azide

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C.

Target Details for Insulin Receptor

Target: Insulin Receptor (INSR)

Alternative Name: INSR / Insulin Receptor

Background: Name/Gene ID: INSR
Subfamily: Insulin receptor
Family: Protein Kinase

Synonyms: INSR, CD220, ILP receptor, Insulin receptor, IR, HHF5, CD220 antigen

Gene ID: 3643

UniProt: P06213

Pathways: NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity