Integrin beta 2 antibody

Catalog No. ABIN600732

The Rat Monoclonal anti-Integrin beta 2 antibody (ABIN600732) specifically detects Integrin beta 2 in FACS, IP, IHC and IHC (fro). The antibody is reactive with Human and Dog samples.

Quick Overview for Integrin beta 2 antibody (ABIN600732)

Target: Integrin beta 2 (ITGB2)

Reactivity: Human, Dog

Host: Rat

Clonality: Monoclonal

Conjugate: This Integrin beta 2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Integrin beta 2 Antibody

Specificity: Recognizes human CD18. Species cross-reactivity: canine.

Purification: Protein G purified

Immunogen: Human neutrophils.

Type of Immunogen: Cells

Isotype: IgG2b

Application Details

Application Notes: Approved: Flo (1:50 - 1:100), IHC, IHC-Fr (1:1000 - 1:5000), IP

Usage: Suitable for use in Flow Cytometry, Immunohistochemistry (frozen), and Immunoprecipitation. Flow Cytometry: 1:50-1:100, 10 μL labels 10^6 cells in 100 μL. Immunohistochemistry (frozen): 1:1000-1:5000.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. For long-term storage and to avoid freeze-thaw cycles, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 1 year at -20°C.

Target Details for Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Alternative Name: ITGB2 / MAC-1 / CD18

Background: Name/Gene ID: ITGB2
Family: Integrin

Synonyms: ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1

Gene ID: 3689

UniProt: P05107

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation