MDM2 antibody

Catalog No. ABIN601926

This anti-MDM2 antibody is a Rabbit Polyclonal antibody detecting MDM2 in IHC. Suitable for Human, Rat, Monkey, Dog, Rabbit and Horse.

Quick Overview for MDM2 antibody (ABIN601926)

Target: MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))

Reactivity: Human, Rat, Monkey, Dog, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MDM2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-MDM2 Antibody

Specificity: Recognizes human MDM2.

Purification: Immunoaffinity purified

Immunogen: Synthetic non-phosphopeptide corresponding to human MDM2 around the phosphorylation site of Serine 166 (A-I-SP-E-T).

Type of Immunogen: Synthetic Non-phosphopeptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC (1:50 - 1:100)

Usage: Suitable for use in Immunohistochemistry: 1:50-1:100.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for MDM2

Target: MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))

Alternative Name: MDM2

Background: Name/Gene ID: MDM2

Synonyms: MDM2, ACTFS, Double minute 2 protein, Hdm2, MDM2 variant FB30, HDMX, Oncoprotein Mdm2, p53-binding protein Mdm2, MDM2 variant FB28

Gene ID: 4193

UniProt: Q00987

Pathways: p53 Signaling, PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Autophagy, Ubiquitin Proteasome Pathway