SMARCA4 antibody (AA 2-14)

Catalog No. ABIN609669

Product Details anti-SMARCA4 Antibody

Target: SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))

Binding Specificity: AA 2-14

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Monkey, Bat, Chicken, Hamster, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This SMARCA4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human SMARCA4 / BRG1. This antibody is expected to recognize all reported isoforms (NP_001122321.1, NP_003063.2, NP_001122317.1, NP_001122318.1, NP_001122319.1, NP_001122320.1). Reported variants NP_003063.2 and NP_001122316.1 represent identical protein.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Horse, Rabbit, Pig, Opossum, Chicken, Platypus (100%) Bovine, Xenopus, Stickleback, Pufferfish, Zebrafish (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide STPDPPLGGTPRP-C from the N-terminus of human SMARCA4 / BRG1 (NP_001122321.1, NP_003063.2, NP_001122317.1, NP_001122318.1, NP_001122319.1, NP_001122320.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Horse, Rabbit, Pig, Opossum, Chicken, Platypus (100%), Bovine, Xenopus, Stickleback, Pufferfish, Zebrafish (92%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3.75 - 7.5 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for SMARCA4

Target: SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))

Alternative Name: SMARCA4 / BRG1 (SMARCA4 Products)

Synonyms: SMARCA4 antibody, BAF190 antibody, BAF190A antibody, BRG1 antibody, MRD16 antibody, RTPS2 antibody, SNF2 antibody, SNF2L4 antibody, SNF2LB antibody, SWI2 antibody, hSNF2b antibody, brg-1 antibody, Brg1 antibody, HP1-BP72 antibody, SNF2beta antibody, SW1/SNF antibody, b2b692Clo antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 antibody, SMARCA4 antibody, Smarca4 antibody

Background: Name/Gene ID: SMARCA4

Synonyms: SMARCA4, ATP-dependent helicase SMARCA4, BAF190, BRG1-associated factor 190A, Brahma protein-like 1, BRG1, BRM/SWI2-related gene 1, HSNF2b, MRD16, Protein BRG-1, SNF2-like 4, SNF2LB, SNF2-BETA, SNF2B, SWI2, Nuclear protein GRB1, SNF2, SNF2L4, Transcription activator BRG1, Homeotic gene regulator, Protein brahma homolog 1, RTPS2, Sucrose nonfermenting-like 4

Gene ID: 6597

NCBI Accession: NP_001122321, NP_003063, NP_001122317, NP_001122318, NP_001122319, NP_001122320

UniProt: P51532

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance