Spartan antibody (AA 1-240)

Catalog No. ABIN6148389

Product Details anti-Spartan Antibody

Target: Spartan (C1orf124) (Chromosome 1 Open Reading Frame 124 (C1orf124))

Binding Specificity: AA 1-240

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Spartan antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MDDDLMLALR LQEEWNLQEA ERDHAQESLS LVDASWELVD PTPDLQALFV QFNDQFFWGQ LEAVEVKWSV RMTLCAGICS YEGKGGMCSI RLSEPLLKLR PRKDLVETLL HEMIHAYLFV TNNDKDREGH GPEFCKHMHR INSLTGANIT VYHTFHDEVD EYRRHWWRCN GPCQHRPPYY GYVKRATNRE PSAHDYWWAE HQKTCGGTYI KIKEPENYSK KGKGKAKLGK EPVLAAENKG

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human SPRTN (NP_001010984.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Spartan

Target: Spartan (C1orf124) (Chromosome 1 Open Reading Frame 124 (C1orf124))

Alternative Name: SPRTN (C1orf124 Products)

Synonyms: Spartan antibody, c1orf124 antibody, C1orf124 antibody, DDDL1880 antibody, DVC1 antibody, PRO4323 antibody, dJ876B10.3 antibody, C28H1orf124 antibody, SprT-like N-terminal domain antibody, sprtn antibody, SPRTN antibody

Background: The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.,SPRTN,C1orf124,DVC1,PRO4323,spartan,Epigenetics & Nuclear Signaling,SPRTN

Molecular Weight: 24 kDa/29 kDa/55 kDa

Gene ID: 83932

UniProt: Q9H040