SRGN antibody (AA 28-158)

Catalog No. ABIN6148441

Product Details anti-SRGN Antibody

Target: SRGN (serglycin (SRGN))

Binding Specificity: AA 28-158

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRGN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: YPTRRARYQW VRCNPDSNSA NCLEEKGPMF ELLPGESNKI PRLRTDLFPK TRIQDLNRIF PLSEDYSGSG FGSGSGSGSG SGSGFLTEME QDYQLVDESD AFHDNLRSLD RNLPSDSQDL GQHGLEEDFM L

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 28-158 of human SRGN (NP_002718.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SRGN

Target: SRGN (serglycin (SRGN))

Alternative Name: SRGN (SRGN Products)

Synonyms: PPG antibody, PRG antibody, PRG1 antibody, Prg antibody, Prg1 antibody, Sgc antibody, Pgsg antibody, serglycin antibody, SRGN antibody, Srgn antibody

Background: This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene.,SRGN,PPG,PRG,PRG1,serglycin,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Extracellular Matrix,Bone,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,SRGN

Molecular Weight: 17 kDa

Gene ID: 5552

UniProt: P10124

Pathways: Maintenance of Protein Location