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SFTPB antibody (AA 94-393)

SFTPB Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6147687
  • Target See all SFTPB Antibodies
    SFTPB (Surfactant Protein B (SFTPB))
    Binding Specificity
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 94-393
    Reactivity
    • 31
    • 12
    • 11
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 40
    • 5
    Rabbit
    Clonality
    • 42
    • 3
    Polyclonal
    Conjugate
    • 25
    • 7
    • 5
    • 4
    • 2
    • 2
    This SFTPB antibody is un-conjugated
    Application
    • 41
    • 23
    • 10
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Sequence
    MAKEAIFQDT MRKFLEQECN VLPLKLLMPQ CNQVLDDYFP LVIDYFQNQT DSNGICMHLG LCKSRQPEPE QEPGMSDPLP KPLRDPLPDP LLDKLVLPVL PGALQARPGP HTQDLSEQQF PIPLPYCWLC RALIKRIQAM IPKGALAVAV AQVCRVVPLV AGGICQCLAE RYSVILLDTL LGRMLPQLVC RLVLRCSMDD SAGPRSPTGE WLPRDSECHL CMSVTTQAGN SSEQAIPQAM LQACVGSWLD REKCKQFVEQ HTPQLLTLVP RGWDAHTTCQ ALGVCGTMSS PLQCIHSPDL
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 94-393 of human SFTPB (NP_000533.3).
    Isotype
    IgG
    Top Product
    Discover our top product SFTPB Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SFTPB (Surfactant Protein B (SFTPB))
    Alternative Name
    SFTPB (SFTPB Products)
    Synonyms
    PSP-B antibody, SFTB3 antibody, SFTP3 antibody, SMDP1 antibody, SP-B antibody, AI562151 antibody, SF-B antibody, Sftp-3 antibody, Sftp3 antibody, Sp-b antibody, SFTPB antibody, sftpb antibody, xSP-B antibody, surfactant protein B antibody, surfactant associated protein B antibody, surfactant, pulmonary-associated protein B L homeolog antibody, SFTPB antibody, Sftpb antibody, sftpb.L antibody
    Background
    This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.,SFTPB,PSP-B,SFTB3,SFTP3,SMDP1,SP-B,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,SFTPB
    Molecular Weight
    42 kDa
    Gene ID
    6439
    UniProt
    P07988
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