MAPK8 / MAPK9 (pThr183), (pTyr185) antibody
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- Target
- MAPK8 / MAPK9
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Binding Specificity
- pThr183, pTyr185
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MMTPY
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Phosphorylated Antibodies
- Immunogen
- A synthetic phosphorylated peptide around T183 of human JNK1 (NP_620637.1).
- Isotype
- IgG
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- Application Notes
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MAPK8 / MAPK9
- Alternative Name
- MAPK8/MAPK9
- Background
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016],JNK1/2,Protein phosphorylation,Protein phosphorylation,Protein phosphorylation,MAPK8/MAPK9
- Molecular Weight
- 35 kDa/44 kDa/48 kDa/27 kDa
- Gene ID
- 5599, 5601
- UniProt
- P45983, P45984
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