ABCB11 antibody (AA 600-750)

Catalog No. ABIN6136348

Product Details anti-ABCB11 Antibody

Target: ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))

Binding Specificity: AA 600-750

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCB11 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: VLSKIQHGHT IISVAHRLST VRAADTIIGF EHGTAVERGT HEELLERKGV YFTLVTLQSQ GNQALNEEDI KDATEDDMLA RTFSRGSYQD SLRASIRQRS KSQLSYLVHE PPLAVVDHKS TYEEDRKDKD IPVQEEVEPA PVRRILKFSA P

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 600-750 of human ABCB11 (NP_003733.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ABCB11

Target: ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))

Alternative Name: ABCB11 (ABCB11 Products)

Synonyms: ABCB11 antibody, Bsep antibody, ABC16 antibody, BRIC2 antibody, BSEP antibody, PFIC-2 antibody, PFIC2 antibody, PGY4 antibody, SPGP antibody, Lith1 antibody, BSEP/SPGP antibody, Spgp antibody, ATP binding cassette subfamily B member 11 antibody, bile salt export pump antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 11 antibody, ABCB11 antibody, LOC100489744 antibody, LOC100565276 antibody, EDI_111220 antibody, EDI_272930 antibody, abcb11 antibody, Abcb11 antibody

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.,ABCB11,ABC16,BRIC2,BSEP,PFIC-2,PFIC2,PGY4,SPGP,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,ABCB11

Molecular Weight: 146 kDa

Gene ID: 8647

UniProt: O95342