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ARHGAP44 antibody (AA 666-772)

ARHGAP44 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6137082
  • Target See all ARHGAP44 Antibodies
    ARHGAP44 (rho GTPase Activating Protein 44 (ARHGAP44))
    Binding Specificity
    • 8
    • 8
    • 7
    • 2
    • 1
    AA 666-772
    Reactivity
    • 22
    • 6
    • 5
    Human
    Host
    • 22
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    This ARHGAP44 antibody is un-conjugated
    Application
    • 21
    • 17
    • 15
    • 14
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MADQSAGQPS PVSLSPTPPS TPSPYGLSYP QGYSLASGQL SPAAAPPLAS PSVFTSTLSK SRPTPKPRQR PTLPPPQPPT VNLSASSPQS TEAPMLDGMS PGESMST
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 666-772 of human ARHGAP44 (NP_055674.4).
    Isotype
    IgG
    Top Product
    Discover our top product ARHGAP44 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ARHGAP44 (rho GTPase Activating Protein 44 (ARHGAP44))
    Alternative Name
    ARHGAP44 (ARHGAP44 Products)
    Synonyms
    RICH2 antibody, arhgap44 antibody, NPC-A-10 antibody, 6330543G20 antibody, AI840762 antibody, AU040829 antibody, AW493732 antibody, Rich2 antibody, Rho GTPase activating protein 44 antibody, si:ch211-114m9.1 antibody, ARHGAP44 antibody, si:ch211-114m9.1 antibody, Arhgap44 antibody
    Background
    GTPase-activating protein (GAP that stimulates the GTPase activity of Rho-type GTPases. Thereby, controls Rho-type GTPases cycling between their active GTP-bound and inactive GDP-bound states. Acts as a GAP at least for CDC42 and RAC1. In neurons, is involved in dendritic spine formation and synaptic plasticity in a specific RAC1-GAP activity (By similarity. Limits the initiation of exploratory dendritic filopodia. Recruited to actin-patches that seed filopodia, binds specifically to plasma membrane sections that are deformed inward by acto-myosin mediated contractile forces. Acts through GAP activity on RAC1 to reduce actin polymerization necessary for filopodia formation (By similarity. In association with SHANK3, promotes GRIA1 exocytosis from recycling endosomes and spine morphological changes associated to long-term potentiation (By similarity.,ARHGAP44,NPC-A-10,RICH2,Signal Transduction,G protein signaling,Signal Transduction,ARHGAP44
    Molecular Weight
    83 kDa/88 kDa/89 kDa
    Gene ID
    9912
    UniProt
    Q17R89
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